Tecfidera (dimethyl fumarate) Side Effects, Uses Dosages
Side Effects for Tecfidera (dimethyl fumarate)
Initial chronic diahrea, nausea, stomach cramps itching and flushing: fatigue. lost fatty layer/weight rapidly within days. stopped. restarted after couple of months but taken wih food with a content of saturated fats works better with lessGI effects. The flushing still occurs occasionally.Recently been getting tired after eating. and also tingling itching
second time used 120mg dose for week or two longer before moving onto 240mg tablets. no significant MS relapses or Lesions noted since but only been one year...However, now the 3 monthly blood tests are being run at one monthly tests (for last 3 months) as one of the counts is lower...
I tried Betaseron and Avonex which did nothing for me. Tecfidera was a brand new drug in 2013 that my neuro suggested. Worked wonders for me. No new lesions and I felt almost normal for years. White blood cell count went down so I have to try a new drug. Devastated.Some tips for side effects.Aspirin for flushing and a big meal fatty meal with each dosage.
I was feeling like I was dead was so tired, couldn't do the things I did normally, extreme pain there was, I was starting to cry because of pain and I got dizzy, there was numbness too. After I quit almost all of them went away sooo we can see that was about the side effects. I wanted the pill to work but it apparently didn't for me.
It was the first pill I gave up because of bad side effects. Worst side effects experienced with a pill.
So far, so good, have yet to have an MRI to see if it's working. However, from a side effects standpoint it's been great. My neurologist had a very slow titration program and I credit that with the lack of side effects.
Flushing, stomach upset, dry mouth.
This is not medical advice, this is only my experience. Consult a Doctor prior to trying these remedies. To combat the flushing, I would take two low-dose aspirin about an hour before dose. For flushing and stomach upset, I would also try to take it with a meal - at the very least, a full fat greek yogurt, full fat cheese, etc. Protein and fat helped. Nothing helped the dry mouth, and apparently it's not a recorded side effect (although it's the only reason I had dry mouth). Tec nearly cleared my severe Plaque Psoriasis (and made me a happy girl), but after several months Tec did nothing for the MS, having new lesions and/or enhancing lesions on each MRI. Side effects were bothersome and required a bit of planning, but because I had great results with the psoriasis, I tolerated it longer than I would have if I did not have psoriasis.
Initial nausea, stomach cramps and flushing. The stomach issues were so bad that I nearly abandoned it after a week but then it slowly started to subside. The flushing still occurs occasionally and I do still take the tablets with food just in case.
Try avoiding fruit and other acidic foods when first starting on the tablets. I found that a big breakfast helped with the first tablet of the day. I also found that keeping my stomach full helped so constantly eating snacks was how things first started but definitely got better after a month or two.
Transient rash.Forgive me I don't know the dose.
I am exhausted all the time. I have bad nausea as well. I was told to take the meds with a Fat, Carb, and Protein each time 10 minutes or more before taking the pill. That's making me feel full all the time, and tired. I only weigh 125 pounds. I shouldn't be this tired! We will see if it helps with my next MRI. The nausea and tiredness must go away!!!
Initially, flushing and gastrointestinal Taking with food definitely helped. After 4-6 weeks the side effects started to reduce. Now they are rare but I still take with foodJust had my first MRI and things looked good. Have had no relapses (but didn't on Avonex either which I was taking before).I like the independence of tecfidera over the Avonex shots. I just couldn't do it i had to drive over to my mother in law and have her perform the injections. It is nice to feel in control of my therapy.
Terrible fatigue, flushing, nausea for about 6 weeks. Then, only flushing and occasional mild nausea for 15-30 minutes a few hours after each dose. It has been SO worth it! No relapses, MRI improvement and lesion healing :) Overall I feel pretty good considering, and I do not miss shots every day either.
TECFIDERA (DIMETHYL FUMARATE): Dimethyl fumarate is used to treat relapsing forms of multiple sclerosis (MS). It is not a cure for MS. It helps decrease the number of episodes of worsening MS. (Sources: U.S. Centers for Medicare Services, FDA)
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