Otezla (apremilast) Side Effects, Uses Dosages
Side Effects for Otezla (apremilast)
Had the sample dosage pack, when last day of 20 mg started getting a headache. When I started the 30 mg, my head felt like it was blowing off including neck pain. I do get migraines and sinus headaches in the past.
My Rheumatologist said to stay off for a week then begin at 10 mgs every 3rd day.Was fine, no headaches then after 6 dose, I took 10mgs at night.Woke up at 2 am itching all over but no rash. Looked in mirror and my eyelids were swollen?? Took 2 Benadryls and in AM was fine
Not sleeping well and muscle pain in legs causing me to take ibuprofen - this is not a listed side effect
Loose stools, stomach cramps, tiredness, and severe muscle pain. Having to take Ibuprofen to help with pain.
When I first started taking Otezla I would get nauseous and I fixed this by eating half hour before taking it had occasional diarrhea nothing too dramatic up until now when the diarrhea hits me out of the blue without any warning usually an hour or two after taking the pill. Its pretty embarrassing and luckily I been home both times ! I only started to experience this strange event after I caught covid. Is their a connection, no idea but it seems odd.
My PSA is so bad I have to be on Cosentyx and Otezla without this combo I'm bedridden or house bound.
Started on 2 tabs a day. Cleared my severe psoriasis with 3 weeks. After 3 months, psoriasis came back moderately. Legs still clear, arms somewhat clear, face somewhat clear.
Loose bowel movements, the odd headache and feelings of nausea
Only been on it for a month and side effects are subsiding.Psoriasis is the best it's been for years, nearly all clear on body and greatly reduced on scalp
Nausea with my morning dose. Stomach cramping/gas with both doses
Extremely fatigued, depressed, headache, muscle cramps,diarrhea, back and shoulder pain, dry watery eyes,insomnia, elevated pains.
I started Apremilast 2 weeks ago.At first, the side effects were bad - diarrhoea, cramping pains and lots of gas, plus headaches. But they've gone now. I'm still a bit "loose" but I can manage just fine.It's already easing my symptoms so I'm glad I stuck with it
Rough to get used to, but worth it!
Been on this for 10 days already see clearing of the skin with no side effects to speak of.
Psoriatic Arthritis, psoriasis on m
Stomach pain, severe gas within an hour of taking, insomnia ,no appetite, loss of interest in anything.
The psoriasis on my scalp is gone in 30 days. Unsure if it is due to otezlla but I have gotten 2 UTI in 30 days, I also have blisters all over my tongue hurting really bad. Have not notice a difference I. Arthritis pain at all!
Palmar/Plantar Plaque Psoriasis
Had to adjust dose several times due to headache but fine now.No side effects now! Yay!
I am taking 1 every other day and 2 (am and pm) the other day ..my hands and feet cleared up like magic! Soooo happy! Called the Otezla help line and I get it free!
Diarrhea, gas, nausea, vomiting, weight loss, harsh chronic cough, runny nose, sore ears.
lost 10lbs, headaches, and hot flashes... all the time.
it worked great for about 3 months. Cleared my skin completely. But then my psoriasis came back, stayed on the medication for 3 more months before stopping. Within days after stopping otezla all the hot flashing stopped. Gained all the weight back. And no more headaches. I was really excited at first. Now I'm back to square one
Psoriasis, psoriatic arthritis
Can't take more than once a day or extreme side effects. Works good but not happy with excess gas.
Day 8 on starter pack. Skin is less scaly. Started coughing, I have allergies so not sure if its related.
Psoriasis, on my feet, palm of hand
Can't sleep well, lil depression, lost 10lbs, lost of appitite.
I like taking this drug, my hands, feet has healed up very well. I hope I can continue to stay on it. The side effects are not that bad for me, except sleeping. Lost weight, love that. It's working for me
I had headaches from the start, acid reflex, depression, and pain in my jaw.
It helped my psoriasis but not my pain
Nausea after morning dose, sometimes in the evening as well. Bowel issues, insomnia and horrible muscle cramps over my entire body. Slightly raised depression levels. No appetite and not thirsty. Headaches. Dr says keep taking it....hoping for good outcomes for patients
OTEZLA (APREMILAST): This medication is used to treat a certain type of arthritis (psoriatic arthritis). Apremilast is also used to treat a certain type of skin condition (moderate to severe plaque psoriasis). Apremilast belongs to a class of drugs known as phosphodiesterase 4 (PDE4) inhibitors. For the treatment of psoriatic arthritis, it decreases pain and swelling, and may help improve flexibility in the affected joints. For the treatment of plaque psoriasis, it may help to reduce the redness, thickening, and scaling of the skin that occurs with this condition. (Sources: U.S. Centers for Medicare Services, FDA)
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