Elidel (pimecrolimus) Side Effects, Uses Dosages
Side Effects for Elidel (pimecrolimus)
I was prescribed this medication for perioral dermatitis (POD). It is the only treatment so far that has helped my symptoms. After 1 week of applying a thin layer to the effected area of my face, nose and eyes, the itchy, bumpy, red tight, dry rash was almost entirely gone. Just a faint redness remains around the sides of my nose and mouth. I have been applying the cream once daily for the past 9 months. I have tried discontinuing the Elidel for 2-3 days, but the POD begins to return. I wish I could identify and treat the root problem of my POD so that I am not dependent on this medication. But I am happy that I have something that helps. Neither my dermatologist nor I have been able to determine what the underlying cause of my POD is. A 2 month trial of 100mg doxycycline 1x/day was not effective in reducing any of the POD symptoms. My derm. was very surprised by this. I am going to try topical adapelene and azelaic acid. Hopefully one will calm down the POD enough so that I can discontinue the Elidel, which has an application site cancer warning.Update: My dermatologist said that Elidel is safe to use despite what the FDA guidelines say about not using for longer than 2 weeks. My derm. also said that the black box warning it carries for increased risk of melanoma is not true. My derm is a very smart guy who I know personally, so I trust his judgment. I've increased the dose and my POD is remitting again.
I quickly developed allergic hives all over my face. Each hive had a small liquid whitehead in its center. I had to use both topical and systemic antihistamines for 5 days now, and it still has not completely resolved.
If you have sensitive skin, think twice before using this.
ELIDEL (PIMECROLIMUS): Pimecrolimus is used to treat certain skin conditions such as eczema (atopic dermatitis) in people who should not use or have not responded to other eczema medications (e.g., topical steroids). Eczema is an allergic-type condition that causes red, irritated, and itchy skin. This drug works by changing the skin's defense (immune) system, thereby decreasing the allergic reaction that causes eczema. Pimecrolimus belongs to a class of drugs known as topical calcineurin inhibitors (TCIs). This medication is not recommended if you have a history of a certain rare genetic disorder (Netherton's syndrome). Also, this medication should not be used by anyone who has a weakened immune system (e.g., following an organ transplant). (Sources: U.S. Centers for Medicare Services, FDA)
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